Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8723644 | Nutrition | 2018 | 24 Pages |
Abstract
The weight loss that was induced by RYGB surgery alters the mTOR signaling pathway and specifically the mTOR complex 2 subunit. The increased expression of genes that act in this pathway such as RICTOR, PIK3 R1, and HIF1 A reflects the induced weight loss and improved metabolic indicators (e.g., insulin resistance and lipolysis) that are evidenced in this study.
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Authors
Marcela Augusta de Souza Ph.D., Carolina Ferreira Ph.D., Natalia Yumi M.Sc., Bruno Affonso Parenti M.Sc., Cristiana M.Sc., Wilson M.D., Ph.D., Wilson Araujo M.D., Ph.D., Doroteia Rossi Silva Ph.D., Julio Sergio M.D., Ph.D., Carla Barbosa Ph.D.,