Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8723662 | Nutrition | 2018 | 8 Pages |
Abstract
Using advanced micellation technology, stable solubilisates of curcumin and boswellia extracts with markedly enhanced bioavailability were prepared. The drugs were given daily for 3 weeks, starting from the day of Freund complete adjuvant innoculation. Solubilized curcumin showed a reduction in paw volume, tumor necrosis factor-α, interleukin-6 and C-reactive protein, myloperoxidase and lipid peroxidation markers as well as an increase in total antioxidant capacity, an effect which wass equivalent to diclofenac. The native forms showed no significant effect compared to control untreated groups.
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Authors
Mohamed T. Ph.D., Rania M. Ph.D., Walaa A. Ph.D., Jan Ph.D., Dariush Dipl.Ing., Mona Dr.rer.nat.,