Among Patients With Nonalcoholic Fatty Liver Disease, Modest Alcohol Use Is Associated With Less Improvement in Histologic Steatosis and Steatohepatitis

Article ID	Journal	Published Year	Pages	File Type
8724737	Clinical Gastroenterology and Hepatology	2018	15 Pages	PDF

Abstract

In a longitudinal analysis of liver biopsies from patients with NAFLD not receiving pharmacologic therapy, modest alcohol use was associated with less improvement in steatosis and level of aspartate transaminase, as well as lower odds of NASH resolution, compared with no use of alcohol.

Keywords

NAFLD NASH CRN HOMA-IR Alcohol Use Disorders Identification Test AST Aspartate aminotransferase homeostasis model assessment of insulin resistance Nonalcoholic fatty liver disease Audit body mass index BMI nonalcoholic steatohepatitis clinical research network Long-term Cohort study Resolution Fatty liver Flint

Related Topics

Health Sciences Medicine and Dentistry Gastroenterology

Preview

Among Patients With Nonalcoholic Fatty Liver Disease, Modest Alcohol Use Is Associated With Less Improvement in Histologic Steatosis and Steatohepatitis

Authors

Veeral Ajmera, Patricia Belt, Laura A. Wilson, Ryan M. Gill, Rohit Loomba, David E. Kleiner, Brent A. Neuschwander-Tetri, Norah Terrault, Nonalcoholic Steatohepatitis Clinical Research Network Nonalcoholic Steatohepatitis Clinical Research Network,