| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8725365 | Clinical Gastroenterology and Hepatology | 2017 | 26 Pages |
Abstract
In a population-based study of patients in Denmark with IBD and SBC, we found risk of adenocarcinomas and neuroendocrine tumors to be increased among persons with Crohn's disease. Most patients with IBD-SBC had extensive IBD of moderate-to-severe activity. Adenocarcinomas appeared to develop via an inflammation-dysplasia-carcinoma pathway, but differed from IBD-related colorectal adenocarcinomas in their molecular features.
Keywords
MMRNational Patient RegisterDCRSBASBCNPRIBDDPRH&ESmall bowel adenocarcinomaImmunohistochemistryIHCCrohn’s diseaseInflammatory bowel diseasemismatch repairNeuroendocrine tumorNETICDDanish Cancer Registryintestinal cancerColorectal cancerSmall bowel cancerInternational Classification of DiseasesHematoxylin and EosinCRCUlcerative colitis
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Authors
Rasmus Dahlin Bojesen, Lene Buhl Riis, Estrid Høgdall, Ole Haagen Nielsen, Tine Jess,