| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8726369 | Gastroenterology | 2018 | 18 Pages |
Abstract
ARID1A regulates expression of SOX9, activation of the mTOR pathway, and differentiation of PDCs. ARID1A inhibits formation of PDACs from IPMNs in mice with pancreatic expression of activated KRAS and is down-regulated in IPMN and PDAC tissues from patients.
Keywords
PI3KPDCMCNIPMN3-dimensionalAdenosine TriphosphateATPPancreatic ductal adenocarcinomaPDAC یا pancreatic ductal adenocarcinomaOncogeneTumorigenesis2-dimensionalTranscriptional regulatorPancreatic cancerPhosphatidylinositol 3-kinaseintraductal papillary mucinous neoplasmmucinous cystic neoplasmpancreatic intraepithelial neoplasiawild typePanINPERK
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Authors
Yoshito Kimura, Akihisa Fukuda, Satoshi Ogawa, Takahisa Maruno, Yutaka Takada, Motoyuki Tsuda, Yukiko Hiramatsu, Osamu Araki, Munemasa Nagao, Takaaki Yoshikawa, Kozo Ikuta, Takuto Yoshioka, Zong Wang, Haruhiko Akiyama, Christopher V. Wright,