| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8726498 | Gastroenterology | 2018 | 38 Pages |
Abstract
In a systematic analysis of variants in 23 PID-associated genes, we confirmed the association of variants in XIAP with CD. Further screenings for CD-associated variants and analyses of their functions could increase our understanding of the relationship between PID-associated genes and CD pathogenesis.
Keywords
Candidate gene approachMDPLPSmuramyl dipeptideHTSPBMCPIDORFeQTLIBDMendelian DisorderinterleukinExpression quantitative trait lociCrohn's diseaseInflammatory bowel diseaseEnzyme-linked immunosorbent assayELISAHigh-throughput sequencingPeripheral blood mononuclear cellComplex traitopen reading framelipopolysaccharideGenome-wide association studyGWASSingle nucleotide polymorphismSNPprimary immunodeficiency
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Authors
Leila Amininejad, Benoit Charloteaux, Emilie Theatre, Claire Liefferinckx, Julia Dmitrieva, Pierre Hayard, Vincianne Muls, Jean-Marc Maisin, Michael Schapira, Jean-Michel Ghislain, Pierre Closset, Mehdi Talib, Marc Abramowicz, Yukihide Momozawa,