P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts

Article ID	Journal	Published Year	Pages	File Type
8726501	Gastroenterology	2018	68 Pages	PDF

Keywords

α-SMA PDGF TGF ChIP-qPCR SCID CCl4 CTGF VEGFA shRNA RNA-seq GFP CRE HSC small hairpin RNA Epigenetic modification α-smooth muscle actin Immunofluorescence Chromatin remodeling transforming growth factor Western blot analysis RNA sequencing Hepatic stellate cell Conditioned medium Transcription factor Vascular endothelial growth factor A Connective tissue growth factor platelet-derived growth factor Mechanotransduction Myofibroblast green fluorescent protein Tumor progression Carbon tetrachloride Cre recombinase severe combined immunodeficiency

Related Topics

Health Sciences Medicine and Dentistry Gastroenterology

Preview

P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts

Authors

Changwei Dou, Zhikui Liu, Kangsheng Tu, Hongbin Zhang, Chen Chen, Usman Yaqoob, Yuanguo Wang, Jialing Wen, Jan van Deursen, Delphine Sicard, Daniel Tschumperlin, Hongzhi Zou, Wei-Chien Huang, Raul Urrutia, Vijay H. Shah, Ningling Kang,