JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice

Article ID	Journal	Published Year	Pages	File Type
8726766	Gastroenterology	2018	72 Pages	PDF

Keywords

MEF IKK HMGB1 LC3 PARP GPCR V-ATPase MPSC GPX NAC GSH HCQ MTC NaA RCD IKKβ SQSTM1 sequestosome 1 LPS MLKL TNF PBS NF-κB HPDE PDAC یا pancreatic ductal adenocarcinoma Drug development Targeted therapy RIPK light chain 3 tumor necrosis factor Nuclear factor-kappa B Phosphate buffered saline lactate dehydrogenase LDH lipopolysaccharide anion exchanger regulated cell death mouse embryonic fibroblast monocarboxylate transporter Tumor microenvironment N-acetyl cysteine hydroxychloroquine Pancreas poly (ADP-ribose) polymerase High mobility group box 1 Carbonic anhydrase Glutathione glutathione peroxidase G protein-coupled receptor

Related Topics

Health Sciences Medicine and Dentistry Gastroenterology

Preview

JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice

Authors

Xinxin Song, Shan Zhu, Yangchun Xie, Jiao Liu, Lingyi Sun, Dexing Zeng, Pengcheng Wang, Xiaochao Ma, Guido Kroemer, David L. Bartlett, Timothy R. Billiar, Michael T. Lotze, Herbert J. Zeh, Rui Kang, Daolin Tang,