Combination of Gene Expression Signature and Model for End-Stage Liver Disease Score Predicts Survival of Patients WithÂ Severe Alcoholic Hepatitis

Article ID	Journal	Published Year	Pages	File Type
8726897	Gastroenterology	2018	55 Pages	PDF

Abstract

We integrated data on baseline liver gene expression pattern and the MELD score to create the gs-MELD scoring system, which identifies patients with severe AH, treated or not with corticosteroids, most and least likely to survive for 90 and 180 days.

Keywords

FDA AIC HRS AUC FFPE Ethanol Transcription Food and Drug Administration hepatorenal syndrome Cirrhosis confidence interval formalin-fixed, paraffin-embedded area under the receiver operating characteristic curve Model for End-Stage Liver Disease Akaike’s information criterion hazard ratio Alcoholic hepatitis MELD

Related Topics

Health Sciences Medicine and Dentistry Gastroenterology

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Combination of Gene Expression Signature and Model for End-Stage Liver Disease Score Predicts Survival of Patients WithÂ Severe Alcoholic Hepatitis

Authors

Eric Trépo, Nicolas Goossens, Naoto Fujiwara, Won-Min Song, Antonio Colaprico, Astrid Marot, Laurent Spahr, Pieter Demetter, Christine Sempoux, Gene Y. Im, Joan Saldarriaga, Thierry Gustot, Jacques DeviÃ¨re, Swan N. Thung, Charlotte Minsart,