Article ID Journal Published Year Pages File Type
8726908 Gastroenterology 2018 14 Pages PDF
Abstract
PDAC cells produce IL35 to recruit monocytes via CCL5 and induce macrophage to promote angiogenesis via expression of CXCL1 and CXCL8. IL35 signaling promotes angiogenesis and growth of xenograft tumors from PDAC cells in mice. IL35 might serve as a therapeutic target for patients with pancreatic cancer.
Related Topics
Health Sciences Medicine and Dentistry Gastroenterology
Authors
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