Deficiency of the Mitochondrial NAD Kinase Causes Stress-Induced Hepatic Steatosis in Mice

Article ID	Journal	Published Year	Pages	File Type
8727102	Gastroenterology	2018	59 Pages	PDF

Keywords

ALT RER MTX NCD VCO2 Sirtuins AHF SIRT PPARα GSSG CREBH FFA GSH PBS DECR NADPH NAFLD VO2 NADP Mn-SOD ROS AST Aspartate aminotransferase Liver injury Alanine aminotransferase Steatohepatitis Free fatty acid Fatty acid oxidation Nonalcoholic fatty liver disease triglyceride intraperitoneal normal chow diet Nicotinamide riboside FAO Methotrexate Phosphate-buffered saline Mouse model NAD knockout Respiratory exchange ratio wild type nicotinamide adenine dinucleotide nicotinamide adenine dinucleotide phosphate polymerase chain reaction PCR Palmitic acid reduced glutathione oxidized glutathione Reactive oxygen species peroxisome proliferator-activated receptor α

Related Topics

Health Sciences Medicine and Dentistry Gastroenterology

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Deficiency of the Mitochondrial NAD Kinase Causes Stress-Induced Hepatic Steatosis in Mice

Authors

Kezhong Zhang, Hyunbae Kim, Zhiyao Fu, Yining Qiu, Zhao Yang, Jiemei Wang, Deqiang Zhang, Xin Tong, Lei Yin, Jing Li, Jianmei Wu, Nathan R. Qi, Sander M. Houten, Ren Zhang,