Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8733715 | Critical Reviews in Oncology/Hematology | 2018 | 17 Pages |
Abstract
the review shows the rapid drifting in the management of ALK+ NSCLC patients and the importance of fully understanding and acknowledging the role of the resistance mutation, primary or acquired. We strongly advocate a comprehensive genomic approach in the management of ALK+ NSCLC patients who develop resistance mutations that are still targetable by a different ALK inhibitor.
Keywords
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Authors
Alfredo Addeo, Fabrizio Tabbò, Tim Robinson, Lucio Buffoni, Silvia Novello,