Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8734654 | Revista Brasileira de Hematologia e Hemoterapia | 2017 | 7 Pages |
Abstract
The lack of systemic oxidative imbalance demonstrated by thiobarbituric acid reactive species is correlated to the observation of normal FoxO3 gene expression in mononuclear cells of peripheral blood. However, an imbalanced antioxidant state was shown by the erythrocyte catalase activity/hemoglobin ratio in beta-thalassemia minor carriers. It would be necessary to study FoxO3 gene expression in reticulocytes to elucidate the role of FoxO3 in this pathology.
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Authors
Sandra Stella Lazarte, MarÃa Eugenia Mónaco, Magdalena MarÃa Terán, Ana Cecilia Haro, Miryam Emilse Ledesma Achem, Blanca Alicia Issé,