Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8734981 | Transfusion and Apheresis Science | 2018 | 5 Pages |
Abstract
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) still remains to be the curative treatment option for various non-malignant and malignant hematopoietic diseases. The outcome of allo-HSCT primarily depends on the engraftment of the graft. Graft failure (GF), is a life-threatening complication which needs the preferential therapeutic manipulation. In this paper, we focused on the definitions of graft failure / poor graft function and also we reviewed the current understanding of the pathophysiology, risk factors and treatment approaches for these entities.
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Authors
Zehra Narli Ozdemir, Sinem Civriz BozdaÄ,