Alarmed or unalarmed!! Donor red cell lysis during plateletpheresis procedure

Plateletpheresis procedures are considered safe for donors and very few adverse events are reported. Donor related adverse events include hypo-calcemia due to citrate toxicity, vasovagal reactions, transient post-procedural decline in hemoglobin, hematocrit and platelet count. Kit related adverse events include damage of the kit or rarely mechanical damage of the red cells during procedure. This damage can lead to failure of the rinse-back of the red cells to the donors causing higher red cell loss in such donors. Here, we are reporting a kit related adverse event that led to donor red cell lysis during plateletpheresis procedure.