Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8735645 | Journal of Clinical and Experimental Hepatology | 2018 | 33 Pages |
Abstract
Strong positivity for GS is a highly sensitive marker for HCC in a cirrhotic background regardless of the differentiation of the tumor in Indian population. This may be due to preferential activation of Wnt pathway in Indian patients with cirrhosis. The sensitivity of the panel was too low for detecting HCCs arising in non-cirrhotic livers, even in the pre-cirrhotic chronically inflamed livers, even though the specificity was high. GPC3 and HSP70 appear to be useful as individual markers for HCCs arising in non-cirrhotic livers.
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Authors
Preithy Uthamalingam, Ashim Das, Arunanshu Behra, Naveen Kalra, Yogesh Chawla,