Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8737168 | Diagnostic Microbiology and Infectious Disease | 2018 | 14 Pages |
Abstract
In direct acting antiviral (DAA)-treated HCV genotype 1, the sustained virologic response rate with the âG/âG genotype of IFNL4 rs368234815 (86.8%) was significantly lower than with âG/TT (95.9%, P = 0.03) or TT/TT (98.6%, P = 0.01). The SVR odds ratio for âG/âG compared to TT/TT was 0.10 (P = 0.03). IFNL4 genotype might predict DAA-response.
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Authors
Lisa I. Backus, Troy A. Shahoumian, Pamela S. Belperio, Mark Winters, Ludmila Prokunina-Olsson, Thomas R. O'Brien, Mark Holodniy,