Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8737233 | Diagnostic Microbiology and Infectious Disease | 2018 | 18 Pages |
Abstract
The amikacin plus gentamicin-containing SuperAminoglycoside medium was developed for screening multiple-aminoglycoside resistance in Gram-negative bacteria (Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii). It was evaluated using aminoglycoside-susceptible (n=12) and aminoglycoside-resistant (n=59) Gram-negative isolates, including 16S rRNA methylase producers (n=20). Its sensitivity and specificity of detection were, respectively, of 95% and 96% for detecting multiple aminoglycoside-resistant methylase producers.
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Authors
Patrice Nordmann, Alain Mazé, Esther Culebras, Jan Dobias, Aurélie Jayol, Laurent Poirel,