Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8737567 | Human Immunology | 2018 | 13 Pages |
Abstract
We report HLA-A, -C, -B, -DRB1, -DQB1 and -DPB1 allele frequencies and estimated haplotype frequencies from 4514 healthy Norwegians who volunteered to participate in the Norwegian Bone Marrow Donor Registry. HLA genotyping was conducted on a Next Generation Sequencing platform. Data were analyzed using Arlequin and Pypop software. No significant deviations from Hardy-Weinberg Equilibrium were noted at any of the loci studied. We discuss the representability for the Norwegian population and argue that the presented HLA data could serve as a Norwegian reference panel.
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Authors
Asgeir Lande, Irene Andersen, Torstein Egeland, Benedicte A. Lie, Marte K. Viken,