Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8737702 | Human Immunology | 2018 | 12 Pages |
Abstract
The avidity of allo-HLA-cross-reactive virus-specific memory CD8+ T cells is therefore highly dependent on epitope expression, and as a consequence, can be both higher and lower for allogeneic versus viral targets under different (patho)physiological conditions.
Keywords
HUVECTCR avidityEBV-LCLPhytohaemagglutininITAMpeptide-MHCpMHCIFNγVZVSSPFCSSSOTCrPHAFACSmAbPBMCCRAFITCsequence-specific oligonucleotideβ-mercaptoethanolSequence-specific primerFörster resonance energy transferFRETinterferon γEnzyme-linked immunosorbent assayELISASurface plasmon resonanceSPRfluorescence-activated cell sortingFluHuman serumfetal calf serumHuman umbilical vein endothelial cellPeripheral blood mononuclear cellcytomegalovirusCMVphycoerythrinfluorescein isothiocyanateimmunoreceptor tyrosine-based activation motifpolymerase chain reactionPCRInfluenza virusVaricella zoster virusMonoclonal antibodiesTransplantationT-cell receptor
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Authors
Heleen van den Heuvel, Kirstin M. Heutinck, Ellen M.W. van der Meer-Prins, Marry E.I. Franke-van Dijk, Paula P.M.C. van Miert, Xiaoqian Zhang, Ineke J.M. ten Berge, Frans H.J. Claas,