| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8738363 | Immunology Letters | 2018 | 8 Pages |
Abstract
- Damaged and activated cells in the disease microenvironment release chemokines and other chemo-attractants.
- Innate and adaptive immune cells migrate into the evolving lesions leading to an immune- fibrotic pathology.
- Progenitor cells and other fibroblast precursors also recruited into the sites of fibrosis.
- Antagonists of chemokines may benefit by reducing cellular recruitment and preventing the immune-fibrotic interaction.
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Authors
Jamie King, David Abraham, Richard Stratton,