Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8738734 | International Journal of Antimicrobial Agents | 2018 | 15 Pages |
Abstract
In this study, we assessed the selective effect of colistin administered orally to healthy weaned piglets harbouring an intestinal mcr-1-positive Escherichia coli strain. Maximum recommended dose and a higher dose often used in European pig farms were given by gavage. No selection of the mcr-1-positive strain was observed in our controlled conditions, irrespective of the dose. Further investigations in real farming conditions seem necessary.
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Authors
Alexis Viel, Jérôme Henri, Agnès Perrin-Guyomard, Julian Laroche, William Couet, Nicolas Grégoire, Michel Laurentie,