Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8739591 | Journal of Autoimmunity | 2018 | 10 Pages |
Abstract
CD4+CD28+KIR+CD11ahi T cells are demethylated and characterized by pro-inflammatory epigenetic and transcriptional profiles in lupus. Eliminating these cells or blocking their pro-inflammatory characteristics might present a novel therapeutic approach for lupus.
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Authors
Elizabeth Gensterblum, Paul Renauer, Patrick Coit, Faith M. Strickland, Nathan C. Kilian, Shaylynn Miller, Mikhail Ognenovski, Jonathan D. Wren, Pei-Suen Tsou, Emily E. Lewis, Kathleen Maksimowicz-McKinnon, W. Joseph McCune, Bruce C. Richardson,