Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8740130 | Journal of Hospital Infection | 2018 | 14 Pages |
Abstract
This article describes the emergence of resistance and predictors of fatality for 1556 cases of healthcare-associated Gram-negative bloodstream infection in 2014 and 2015. The colistin resistance rate in Klebsiella pneumoniae was 16.1%, compared with 6% in 2013. In total, 660 (42.4%) cases were fatal. The highest fatality rate was among patients with Acinetobacter baumannii bacteraemia (58%), followed by Pseudomonas aeruginosa (45%), Klebsiella pneumoniae (41%), Enterobacter cloacae (32%) and Escherichia coli (28%). On multi-variate analysis, the minimum inhibitory concentrations for carbapenems [odds ratio (OR) 1.02, 95% confidence interval (CI) 1.01-1.04; PÂ =Â 0.002] and colistin (OR 1.1, 95% CI 1.03-1.17; PÂ =Â 0.001) were found to be significantly associated with fatality.
Keywords
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Authors
M. Aydın, Ã. Ergönül, A. Azap, H. Bilgin, G. Aydın, S.A. ÃavuÅ, Y.Z. DemiroÄlu, H.E. AlıÅkan, O. MemikoÄlu, Å. MenekÅe, Å. Kaya, N.A. Demir, Ä°. KaraoÄlan, S. BaÅaran, Ã. HatipoÄlu, Å. Erdinç, E. Yılmaz, A. Tümtürk, H. Akalın,