Individual background factors associated with vaccination for seasonal influenza in Japanese schoolchildren

There is little evidence about how individual background factors affect seasonal influenza vaccination of children. At the end of the 2014/2015 influenza season, a cross-sectional questionnaire survey of all elementary schoolchildren in 29 schools in Matsumoto City, Japan, was conducted to obtain information about vaccine uptake activity and individual background factors. Of the 10,524 subjects who responded, 5063 (48.1%) had been vaccinated. Grade in school, underlying disease, number of siblings, and diagnosis with and vaccination for influenza during the previous influenza season differed significantly in vaccinated and unvaccinated groups. Multivariate logistic regression showed that underlying disease and vaccination during the previous influenza season was associated with a higher rate of vaccination, whereas higher grade in school and having ≥3 siblings was associated with a lower rate of vaccination. The findings may be useful to promote a vaccination policy recommending financial support to households with many children or to encourage higher uptake of vaccination in higher grade children.