Article ID Journal Published Year Pages File Type
8741693 Osteoarthritis and Cartilage 2018 32 Pages PDF
Abstract
Contrary to prior reviews, our analysis showed that bisphosphonates neither provide symptomatic relief nor defer radiographic progression in knee OA. However, these agents may still be beneficial in certain subsets of patients who display high rates of subchondral bone turnover. Future studies should be directed at defining such OA subsets and investigating the effects of bisphosphonates in those patients.
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