| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8741711 | Osteoarthritis and Cartilage | 2018 | 33 Pages |
Abstract
TSG-6 activity is a global inflammatory biomarker in knee OA SF. IαI, supplied from outside cartilage, only penetrates the cartilage surface, restricting TSG-6 activity (HC transfer) to this region. Therefore, unopposed TSG-6 in intermediate and deep regions of OA cartilage could possibly block matrix assembly, leading to futile synthesis and account for increased risk of OA progression.
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Authors
C.-H. Chou, D.E. Attarian, H.-G. Wisniewski, P.A. Band, V.B. Kraus,