Article ID Journal Published Year Pages File Type
8741750 Osteoarthritis and Cartilage 2018 34 Pages PDF
Abstract
Disease progression in the MMT model progresses sequentially through changes in the cartilage articular surface, extracellular matrix composition, and then osteophyte mineralization and subchondral bone sclerosis. Cartilage surface roughness is a quantitative, early indicator of degenerative joint disease in small animal OA models and can potentially be used to evaluate therapeutic strategies.
Keywords
Related Topics
Health Sciences Medicine and Dentistry Immunology, Allergology and Rheumatology
Preview
Contrast enhanced μCT imaging of early articular changes in a pre-clinical model of osteoarthritis
Authors
, , , , ,