Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8743775 | Transplant Immunology | 2018 | 35 Pages |
Abstract
P53 gene transfer inhibits coronary artery intimal hyperplasia and reduces the degree of luminal stenosis in transplanted hearts. The inhibitory effect may be related to the wild-type P53 gene-induced apoptosis of vascular smooth muscle cells and inhibition of vascular smooth muscle cell proliferation. This approach is effective and safe and may have good prospects for clinical application.
Keywords
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Immunology
Authors
Li-Ping Wang, Zhi-Bo Jia, Yue Liu, Qiang Gao, Su-Jun Cheng, Di Jin, Lan Ma, Xin-Hua Yin,