Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8743806 | Transplant Immunology | 2018 | 10 Pages |
Abstract
- Recent studies indicate that ATG reduces severe acute and chronic GVHD after PBSCT.
- We evaluated effects of low-dose (2Â mg/kg) ATG-T on T-cell depletion for GVHD prophylaxis after PBSCT.
- Flow cytometric analysis showed the significant depletion of naïve T-cells by low-dose ATG-T.
- ATG-T significantly decreased in absolute numbers of all T-cell subsets evaluated.
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Authors
Souichi Shiratori, Mizuha Kosugi-Kanaya, Eiko Hayase, Kohei Okada, Hideki Goto, Junichi Sugita, Masahiro Onozawa, Masao Nakagawa, Kaoru Kahata, Daigo Hashimoto, Tomoyuki Endo, Takeshi Kondo, Takanori Teshima,