| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8743814 | Transplant Immunology | 2017 | 7 Pages |
Abstract
Our results indicate that tissue-resident NKT cells, but not other lymphocyte populations are responsible for the injury in hepatic IRI. Targeting the activation of NKT cells and/or their effector apparatus would be a novel approach in protecting the liver during transplantation and resection surgery; this may allow us to expand our current criteria for surgery.
Keywords
DAMPsIgMTNFNKTDCDTregTCrnatural killerIRIIschemia-reperfusion injuryAcute liver injuryDonation after cardiac deathimmunoglobulin MinterferonIFNinterleukinLiver surgerystandard error of the meandanger associated molecular patternsnatural killer T cellT cellsT helper cellNKT cellsNatural killer cellstumour necrosis factorMHCmajor histocompatibility complexSEMTransplantationT cell receptor
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
James A. Richards, Stephen J. Wigmore, Stephen M. Anderton, Sarah E.M. Howie,