Assessment of weaning failure in chronic obstructive pulmonary disease patients under mechanical ventilation in Zagazig University Hospitals

1-Myocardial ischemia, delirium, hypomagnesemia, hypophosphatemia and VAP could be considered as important risk factors for weaning failure, however high TSH level >2.65 mIU/ml and abnormal nutritional state were the most valuable independent predictors for weaning failure. 2-An increase in the degree of severity of illness on ICU admission (guided by APACHE II score), previous mechanical ventilation and longer duration of mechanical ventilation could intensify the risk for weaning failure. 3-RSBI below 85 breaths/min/L may increase the rate of weaning success.