Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8745839 | Indian Journal of Tuberculosis | 2018 | 18 Pages |
Abstract
The prevalence of MDR M. tuberculosis was 5.6% in TBM patients with the most common mutation being ÎWT band with S315T1 for INH and ÎWT band with S531T for RMP. MGIT DST was found to be more sensitive for detecting overall resistance in M. tuberculosis but inclusion of LPA not only reduced time for early initiation of appropriate treatment but also enabled detection of heteroresistance in 8 (4%), 2 (1%) isolates for INH and RMP respectively.
Keywords
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Authors
Renu Gupta, Rajeev Thakur, Suman Kushwaha, Nupur Jalan, Pumanshi Rawat, Piyush Gupta, Amitesh Aggarwal, Meena Gupta, Vikas Manchanda,