Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8746107 | Journal of Global Antimicrobial Resistance | 2018 | 26 Pages |
Abstract
INH resistance was spread widely and transmission of INH-resistant isolates, especially with katG315T mutation, was confirmed. Therefore, it is important to diagnose katG315T mutants among INH-resistant strains as it may be a risk factor for subsequent development of multidrug-resistant TB (MDR-TB). Prompt detection of patients with INH-resistant strains would expedite modification of treatment regimens, and appropriate infection control measures could be taken in time to diminish the risk of further development and transmission of MDR-TB.
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Authors
Chitra Alagappan, Smita Sunil Shivekar, Usharani Brammacharry, Vidya Raj Cuppusamy Kapalamurthy, Anbazhagi Sakkaravarthy, Rathinasamy Subashkumar, Muthuraj Muthaiah,