Article ID Journal Published Year Pages File Type
8746279 Journal of Global Antimicrobial Resistance 2018 4 Pages PDF
Abstract
The presence of PAβN resulted in an increase in carbapenem MICs unrelated to efflux pump inhibition, and a decrease in the expression of ompK35 and ompK36 genes without an obvious difference in OMP profiles observed by SDS-PAGE. Therefore, additional factors are responsible for the increase in carbapenem MIC in the presence of PAβN.
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Related Topics
Life Sciences Immunology and Microbiology Applied Microbiology and Biotechnology
Preview
The efflux pump inhibitor phenylalanine-arginine β-naphthylamide (PAβN) increases resistance to carbapenems in Chilean clinical isolates of KPC-producing Klebsiella pneumoniae
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