Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8746400 | Journal of Global Antimicrobial Resistance | 2017 | 26 Pages |
Abstract
The CTX-M-37-producing E. cloacae isolate showed relatively low-level resistance to cefotaxime and the purified enzyme had lower kinetic parameters as the result of Asn114Asp substitution. Presence of an ISEcp1 element and putative promoters upstream of the blaCTX-M-37 gene in E. cloacae, but not in the K. cryocrescens isolate, indicated their roles in mobilisation and expression of the gene.
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Authors
Kyungwon Lee, Dongeun Yong, Seok Hoon Jeong, Khosbayar Tulgaa, Jean-Denis Docquier, Gian Maria Rossolini, Yunsop Chong,