| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8749097 | Microbes and Infection | 2018 | 5 Pages |
Abstract
Previously, we studied an association of two IL28B gene single nucleotide polymorphisms (SNPs) and three IL10 gene SNPs with predisposition to tick-borne encephalitis in a Russian population. In this study, a possible involvement of these SNPs in the development of predisposition to chronic hepatitis C (caused by structurally similar, related virus from the Flaviviridae family) was investigated in the same population. Only the IL10 promoter rs1800872 SNP was associated with predisposition to chronic hepatitis C. This SNP seems to be a common genetic marker of predisposition to two diseases caused by hepatitis C and tick-borne encephalitis viruses in Russian population.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Andrey V. Barkhash, Galina V. Kochneva, Elena V. Chub, Aida G. Romaschenko,