| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8751796 | Virus Research | 2018 | 42 Pages |
Abstract
From 1985 till 2012, variation in the length of the HIV-1 subtype B tat gene is increasingly found in the Dutch epidemic. However, as Tat proteins did not differ significantly in their capacity to stimulate transcription elongation in vitro, the increased HIV-1 virulence seen in recent years could not be linked to an evolving viral Tat protein.
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Authors
Antoinette C. van der Kuyl, Monique Vink, Fokla Zorgdrager, Margreet Bakker, Chris Wymant, Matthew Hall, Astrid Gall, François Blanquart, Ben Berkhout, Christophe Fraser, Marion Cornelissen,