| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8754145 | Asian Pacific Journal of Tropical Medicine | 2017 | 9 Pages |
Abstract
siRNAs directed against NS3 gene significantly decreased mRNA and protein expression in stable cell clones. Viral replication was also vividly decreased in serum infected Huh-7Â cells. Stable Huh-7Â cells expressing NS3 gene is helpful to develop anti-hepatitis C drug screening assays. siRNA therapeutic potential along with other anti-HCV agents can be considered against hepatitis C.
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Authors
Imran Shahid, Waleed Hassan AlMalki, Mohammed Wanees AlRabia, Mohammed Hasan Mukhtar, Shaia Saleh R. Almalki, Saad Ahmed Alkahtani, Sami S. Ashgar, Hani S. Faidah, Muhammad Hassan Hafeez,