Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8755614 | Auris Nasus Larynx | 2013 | 4 Pages |
Abstract
We report an extremely rare case of combined small cell carcinoma (combined SmCC) of the hypopharynx. A 73-year-old male presented with multiple left neck swellings for 1Â month. A tumorous lesion was found in the left pyriform sinus, and biopsy revealed that the lesion was squamous cell carcinoma (SqCC). Surgery was performed and pathological examination led to a diagnosis as combined SmCC, composed of SqCC and small cell carcinoma (SmCC). One month after surgery, a contrast-CT indicated metastases to the cervical lymph node (LN), mediastinum and liver. We performed 5 courses of chemotherapy with the use of cisplatin (CDDP) and irinotecan (CPT-11). The patient temporarily showed a favorable response to the chemotherapy; however, eventually he died of regrowth of the tumor. Combined SmCC is a disease with a poor prognosis. Although biopsy sometimes fails to detect the SmCC component, intensive diagnosis and treatment are necessary.
Keywords
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Medicine and Dentistry (General)
Authors
Nobuhiro Uwa, Tomonori Terada, Takeshi Mohri, Ken Okazaki, Yoshitane Tsukamoto, Seiichi Hirota, Masafumi Sakagami,