Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8758034 | European Journal of Internal Medicine | 2018 | 8 Pages |
Abstract
Idiopathic pulmonary fibrosis (IPF) is a devastating progressive disease associated with a high mortality rate. Novel antifibrotic therapies have been recently demonstrated to slow disease progression and improve survival. However, the management of IPF remains a difficult challenge, since lung complications can still occur, particularly in patients with advanced-stage disease. This paper highlights the most common complications and difficult tasks related to severe IPF such as acute exacerbation of the disease, development of lung cancer, rapid disease progression, and indication for lung transplantation.
Keywords
PO2ARDSPFTHRCTUIPDLCOSVCCBCSpO2BNPENAFVCERSIPFpCO2FEV1TLCNintedanibTRV6-MWTBSA6-minute walk testAntinuclear antibodiesoxygen saturationANAarterial blood gas analysisPulmonary function testPalliationacute exacerbationHigh resolution computed tomographyResidual volumeOxygen therapyForced Expiratory Volume in the first secondLung cancererythrocyte sedimentation ratebody surface areaAcute respiratory distress syndromecomplete blood countdiffusing capacity of the lung for carbon monoxideSlow vital capacityforced vital capacityTotal lung capacityrheumatoid factorAbgOxygen partial pressureCarbon dioxide partial pressureidiopathic pulmonary fibrosisliterTAPSEroom airpolymerase chain reactionPCRC-reactive proteinCRPUsual interstitial pneumoniabrain natriuretic peptidePirfenidoneLung transplantationejection fractiontricuspid annular plane systolic excursion
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Authors
R. Lipsi, D. Mazzola, A. Caminati, D. Elia, C. Lonati, S. Harari,