Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8770069 | American Journal of Kidney Diseases | 2017 | 5 Pages |
Abstract
Crystalline nephropathy can occur following treatment with multiple therapeutic agents. We describe a human immunodeficiency virus (HIV)-infected patient treated for 2 years with combination antiretroviral therapy including atazanavir (ATV). Kidney biopsy revealed a crystalline nephropathy associated with diffuse chronic and granulomatous interstitial inflammation. Following the biopsy, treatment with ATV was discontinued and kidney function returned to pretreatment baseline levels. ATV, which has a well-established association with nephrolithiasis, is a rare but important cause of crystalline nephropathy. Recognition of this association and prompt withdrawal of the offending agent are critical to optimize outcomes.
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Authors
Dominick MD, Majdi MD, Aravinda MD, Julius MD, Vivette D. MD, Glen S. MD,