Article ID Journal Published Year Pages File Type
877107 Medical Engineering & Physics 2008 7 Pages PDF
Abstract

An anastomosis performed in calcified tissues tears up faster than in healthy tissues. This study develops and validates an in vitro non-destructive method to distinguish healthy from calcified aortic tissues.An uniaxial unconfined compression test is able to distinguish healthy from calcified aortas (p<0.01p<0.01). The compressive E  -modulus at a strain level of 10% is 227±34227±34 kPa for artificially calcified and 147±15147±15 kPa for healthy porcine aortic tissues. Calcified aortic tissues have a lower tensile strength than healthy porcine aortic tissues (p<0.05p<0.05). The ultimate tensile strength is 1.34±0.181.34±0.18 MPa and 1.55±0.311.55±0.31 MPa for artificially calcified and healthy porcine aortic tissues respectively. Calcified aortic tissues have a lower resistance to tearing than healthy aortic tissues (p<0.05p<0.05). The resistance to tearing is 1.78±0.331.78±0.33 N/mm and 2.16±0.642.16±0.64 N/mm for artificially calcified and healthy porcine aortic tissues respectively.

Related Topics
Physical Sciences and Engineering Engineering Biomedical Engineering
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