Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8778050 | European Journal of Obstetrics & Gynecology and Reproductive Biology | 2018 | 21 Pages |
Abstract
This is the first report to evaluate the applicability of a commercial NGS-based workflow for preimplantation testing for reciprocal translocations/inversions. Our study demonstrated that NGS can diagnose unbalanced translocation/inversion products with the same efficiency as aCGH. The applicability of NGS, with respect to individual karyotype, can be predicted before proceeding to treatment.
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Authors
Judy F.C. Chow, William S.B. Yeung, Vivian C.Y. Lee, Estella Y.L. Lau, Ernest H.Y. Ng,