Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8778163 | European Journal of Obstetrics & Gynecology and Reproductive Biology | 2018 | 17 Pages |
Abstract
When platelet function was assessed with COX-specific tests that measure the antiplatelet effects of low-dose aspirin and aspirin adherence is accurately accounted for aspirin non-responsiveness was not identified in pregnant women at high-risk of pre-eclampsia. Response to aspirin was not associated with placentally-mediated adverse outcomes. The high-degree of variable and indeterminate aspirin response indicates suboptimal adherence and/or dosing are more pressing factors to address to optimise aspirin effectiveness.
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Authors
Kate Navaratnam, Ana Alfirevic, Andrea Jorgensen, Zarko Alfirevic,