Article ID Journal Published Year Pages File Type
8779790 Fertility and Sterility 2018 6 Pages PDF
Abstract
Deleterious mutations in BRCA1 or BRCA2 genes have long been recognized as independent risk factors, mostly for breast and ovarian cancer. Numerous studies have evaluated the molecular processes involving these genes, the pathophysiology of BRCAness, follow up options and modes of prophylaxis. The fertility of BRCA carriers, however, has not been widely investigated. The aim of the present work is to review the literature pertaining to this issue.
Related Topics
Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health
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