Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8779929 | Fertility and Sterility | 2017 | 8 Pages |
Abstract
Under highly controlled circumstances across 7Â years of data from a single institution, using a uniform uterine preparation, following a precise transfer technique with high-quality day 5-6 slow frozen-thawed blastocysts, a BMI in the overweight range of 25-29.9Â kg/m2 is not associated with a poorer implantation rate or live-birth rate, nor is it associated with an increased risk of miscarriage when compared with a normal BMI range. The increased length of time required during transfer for women with higher BMI suggests body habitus may contribute to difficult transfers, although this may not translate into poorer implantation rates. By using a standardized protocol for slow freezing and thawing of embryos, using identical hormonal preparation and a uniform ET protocol, a homogenous uterine environment was created in this carefully selected cohort of women, thereby minimizing confounders and uniquely highlighting the neutral effect of overweight BMI on implantation rate.
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Authors
Iris G. M.D., Malinda S. M.D., M.B.A., Rebecca M. M.D., M.P.H., Thomas L. M.D.,