Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8780166 | Gynecologic Oncology | 2018 | 5 Pages |
Abstract
In screening for LS in EC, IHC for MMRPs can be performed with identical accuracy on either EMB/C or hysterectomy specimens. Routine testing of diagnostic EMB/Cs may lead to earlier detection of MMRP deficiency, with improved patient uptake of genetic counseling and potential for earlier identification of immunotherapy candidates. Furthermore, reliable IHC-based LS screening performed on EMB/C can guide patient management and genetic counseling in patients unable to undergo hysterectomy.
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Authors
David B. Chapel, S. Diane Yamada, Matthew Cowan, Ricardo R. Lastra,