Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8780652 | Gynecologic Oncology | 2018 | 12 Pages |
Abstract
The existence of EBV(+)HPV(â) carcinomas, the confirmed expression of latent oncoproteins (EBNA1, EBNA2, LMP1) and EBERs in tumor cells, and the association of EBV with the integration of high-risk-HPV DNA in malignant specimens point to EBV as a co-factor (so far underestimated) in the genesis and/or progression of cervical carcinoma. However, further studies are necessary before the link between EBV and cervical carcinoma can be established.
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Authors
Marcos Antonio Pereira de Lima, Pedro Januário Nascimento Neto, LÃvia Peixoto Moreira Lima, Jucier Gonçalves Júnior, Antonio Gilvan Teixeira Junior, Ilara Parente Pinheiro Teodoro, Heberty Tarso Facundo, Cláudio Gleidiston Lima da Silva,