HPV genotype profile in a Norwegian cohort with ASC-US and LSIL cytology with three year cumulative risk of high grade cervical neoplasia

HPV 16 and HPV 33 at baseline both as single or multiple infections, were associated with the highest risk for CIN3 +. Among older women, all 13 high-risk genotypes as single infection were associated with > 20% risk of CIN3 +. Further studies are necessary to risk stratify the individual genotypes to reduce the number of colposcopies in Norway.